thyroid status and dyslipidemia in type 2 diabetic and non-diabetic population

نویسندگان

priti singh lecturer, department of biochemistry, nepalgunj medical college, nepal

salman khan assistant professor, department of microbiology, nepalgunj medical college, nepal

rashmi department of microbiology, kasturba medical college, mangalore, india

rabindra kumar mittal professor, department of biochemistry, nepalgunj medical college, nepal

چکیده

abstract objective: thyroid dysfunction complicates the metabolic derangement observed in diabetes mellitus (dm). it is necessary to recognize and treat it, when present, in order to achieve stability of metabolic control in these patients. the aim of this study was to investigate the effect of dm on thyroid hormone levels and other biochemical variables. materials and methods: to determine the incidence of abnormal thyroid hormone levels in diabetics in nepalgunj medical college and hospital (nepal), blood samples from 100 diabetic subjects and 100 non-diabetic controls were taken between 1st february, 2012 to 31st january, 2013 for investigation of free triidothyronine (ft3), free thyroxine (ft4), thyroid stimulating hormone (tsh), fasting plasma glucose (fpg), serum cholesterol, serum triglycerides, high density lipoprotein (hdl), low density lipoprotein (ldl), very low density lipoprotein (vldl), blood urea, serum creatinine, total protein, albumin, serum glutamate oxaloacetate transaminase (sgot) and serum glutamate pyruvate transaminase (sgpt). results: our findings showed that the level of ft3 and ft4 were significantly lower while the level of tsh was significantly higher in type 2 diabetics as compared to non-diabetics. from the 100 diabetic subjects that were studied, 29% showed abnormal thyroid hormone levels (24% hypothyroidism and 5% hyperthyroidism).the incidence of hypothyroidism was more in females (16%) as compared to males (8%) in type 2 diabetes. conclusion: failure to recognize the presence of these abnormal thyroid hormone levels in diabetics may be a primary cause of poor management often encountered in some treated diabetics.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Thyroid Status and Dyslipidemia in Type 2 Diabetic and Non-Diabetic Population

Abstract Objective: Thyroid dysfunction complicates the metabolic derangement observed in Diabetes Mellitus (DM). It is necessary to recognize and treat it, when present, in order to achieve stability of metabolic control in these patients. The aim of this study was to investigate the effect of DM on thyroid hormone levels and other biochemical variables. Materials and Methods: To determine...

متن کامل

Prevalence of Thyroid Autoantibodies in Type 2 Diabetic Patients

OBJECTIVE: Due to the increased prevalence of thyroid dysfunction in subjects with type 2 diabetes and also this fact that antibodies could potentially identify subjects at risk of thyroid dysfunction, this study was conducted to investigate thyroid autoimmunity in type 2 diabetic patients. MATERIAL AND METHODS: Among patients referred to Yazd Diabetes Research Center, 4000 type 2 diabetic pat...

متن کامل

Gender Differences in Periodontal Status and Oral Hygiene of Non-Diabetic and Type 2 Diabetic Patients

BACKGROUND This study investigated gender dependent differences by the comparison of periodontal status and oral hygiene between diabetic patients and non-diabetic subjects. METHODS 517 mostly obese subjects (171 non-diabetic, 205 type 2 diabetic with oral and 141 with insulin therapy; mean: 59 years) completed an oral hygiene questionnaire and had a clinical examination, including periodonta...

متن کامل

Studies on Dyslipidemia in Diabetic and Non Diabetic Hypertensive Patients

Objective: Background reliable information about the prevalence of dyslipidemia in hypertensive and non hypertensive diabetic patients in local region is essential to the development of regional health policies for prevention and control of this condition. An attempt was made in Puducherry region to examine the lipid profile parameters in the diabetic patients with and without hypertension and ...

متن کامل

Quercetin ameliorates hyperglycemia and dyslipidemia and improves antioxidant status in type 2 diabetic db/db mice

This study investigated the hypoglycemic, hypolipidemic, and antioxidant effects of dietary quercetin in an animal model of type 2 diabetes mellitus. Four-week-old C57BL/KsJ-db/db mice (n = 18) were offered an AIN-93G diet or a diet containing quercetin at 0.04% (low quercetin, LQE) or 0.08% of the diet (high quercetin, HQE) for 6 weeks after 1 week of adaptation. Plasma glucose, insulin, adipo...

متن کامل

Evaluation of Thyroid Dysfunction Among type 2 diabetic Punjabi Population

Diabetes mellitus (DM) is commonly associated with thyroid dysfunction. The aim of the present study was to evaluate the prevalence of thyroid dysfunction in subjects with type 2 diabetes and the effect of type 2 diabetes mellitus on other bio-chemical variables. In the present study 80 type 2 diabetic subjects and 80 healthy non diabetic subjects were investigated for total triidothyronine (T3...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
iranian journal of diabetes and obesity

جلد ۵، شماره ۴، صفحات ۱۳۹-۱۴۳

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023